1. 靶点主信息
| NCBI Gene id: | 23411 |
| Gene_name: | SIRT1 |
| Gene alias: | SIR2; SIR2L1; SIR2alpha |
| Map location: | 10q21.3 |
| Type of gene: | protein-coding |
| Description: | sirtuin 1 |
| OMIM_id: | 604479 |
| HGNC_id: | 14929 |
| Ensembl_id: | ENSG00000096717 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 艾叶 | leaf of Argy Wormwood | Folium Artemisiae Argyi |
| 八角莲 | Dysosmae Verspiellis Rhixoma Et Radix | - |
| 菝葜 | Smilax Chi | - |
| 白扁豆 | White Hyacinth Bean | Semen Lablab Album |
| 白鲳 | Drug Sweetflag | Acorus calamus |
| 白果 | Ginkgo seed | Semen Ginkgo |
| 白果叶 | Ginkgo Leaf | Ginkgo biloba |
| 白花丹参 | Whiteflower Danshen | Salvia miltiorrhiza f. alba |
| 白花甘西鼠尾草 | Radix Salviae Przewalskii Albae | - |
| 白花蛇舌草 | all - grass of Spreading Hedyotis | Herba Hedyotis Diffusae |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 473-98-3 | 白桦脂醇 | Betulin | 72326 |
| 5957-80-2 | 鼠尾草酚 | Carnosol | 442009 |
| 34157-83-0 | 雷公藤红素 | Celastrol | 122724 |
| 458-37-7 | 姜黄素 | Curcumin | 969516 |
| 19057-60-4 | 薯蓣皂苷 | Dioscin | 119245 |
| 497-30-3 | L-(+)-麦角硫因 | Ergothioneine | 5351619 |
| 537-42-8 | 紫檀芪 | Pterostilbene | 5281727 |
| 501-36-0 | 白藜芦醇 | Resveratrol | 445154 |
| 153-18-4 | 芦丁 | Rutin | 5280805 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 30268831 |
| Acute kidney injury | disease | 26348276 |
| Acute kidney injury | disease | 31034781 |
| Acute kidney injury | disease | 21975863 |
| Acute Lung Injury | disease | 25512625 |
| Acute Lung Injury | disease | 28285192 |
| Adenocarcinoma | group | 21550230 |
| Adenocarcinoma | group | 25499851 |
| Adenoma | group | 26223300 |
| Adenomatous Polyposis Coli | disease | 20971552 |
