1. 药材主信息
| 中文名称: | 八角莲 |
| 英文名称: | Dysosmae Verspiellis Rhixoma Et Radix |
| 拉丁名称: | - |
| 使用部位: | - |
| 功用: | - |
| 适用症: | - |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 477-49-6 | 鬼臼脂毒酮 | - | 443014 |
| 506-30-9 | 花生酸 | - | 10467 |
| 1120-36-1 | 1-十四烯 | 1-Tetradecene | 14260 |
| 250268-55-4 | - | 12-O-Acetylphorbol-13-tigliate | 6451045 |
| 250268-56-5 | - | 12-O-Decanoylphorbol-13-(2-methylbutyrate) | 476547 |
| 250268-57-6 | - | 12-O-Tigloylphorbol-13-(2-methylbutyrate) | 6451046 |
| 250268-53-2 | - | 13-O-Acetylphorbol-20-(9Z,12Z)-octadecadienoate | 6451043 |
| 250268-54-3 | - | 13-O-Tigloylphorbol-20-linoleate | 6451044 |
| 80-59-1 | 惕各酸 | 2,3-Dimethylacrylic acid, (E)- | 125468 |
| 1125-21-9 | 2,6,6-三甲基-2-环己烯-1,4-二酮 | 2,6,6-Trimethyl-2-cyclohexene-1,4-dione | 62374 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27017346 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 27017346 |
| CEBPA | C/EBP-alpha; CEBP | 19q13.11 | 29141998 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| DGKD | DGK-delta; DGKdelta; dgkd-2 | 2q37.1 | 28707095 |
| GCG | GLP-1; GLP1; GLP2; GRPP | 2q24.2 | 23471488 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 27017346 |
| MPO | - | 17q22 | 25281414 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Atherosclerosis | disease | 27017346 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Hyperglycemia | disease | 23471488 |
| Hyperglycemia | disease | 28707095 |
| Ischemia | phenotype | 27017346 |
| leukemia | disease | 27270429 |
