科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 靶点主信息

NCBI Gene id: 9507
Gene_name: ADAMTS4
Gene alias: ADAMTS-2; ADAMTS-4; ADMP-1
Map location: 1q23.3
Type of gene: protein-coding
Description: ADAM metallopeptidase with thrombospondin type 1 motif 4
OMIM_id: 603876
HGNC_id: 220
Ensembl_id: ENSG00000158859

2. 相关药材

中文名称 英文名称 拉丁文名称
凹叶厚朴 Twolobed Officinal Mangolia Magnolia biloba
八角茴香 Chinese Star Anise Fructus Anisi Stellati
百合 Bulb of Greenish Lily Bulbus Lilii
白鲜皮 Dictamni Cortex -
半枝莲 all - grass of Barbed Skullcap Herba Scutellariae barbatae
苍术 Rhizome of Swordlike Atractylodes Rhizoma Atractylodis
沉香 Oily wood of Agalloch Eaglewood Lignum Aquilariae Resitum
川黄芩 St Johnswortleaf Skullcap Scutellaria hypericifolia
穿心莲 all-grass of Common Androgrphis Herba andrographitis
滇黄芩 Yunnan Skullcap Scutellaria amoena

3. 相关成分

CAS号 中文名称 英文名称 参考文献
35354-74-6 和厚朴酚 Honokiol 72303
632-85-9 汉黄芩素 Wogonin 5281703

4. 相关疾病

疾病名称 疾病类型 参考文献
Acute Lung Injury disease 21279327
Body Weight phenotype 23623334
Brain Neoplasms group 22259050
Cardiomegaly phenotype 25871545
Colorectal Neoplasms group 24901054
Dyslipidemias group 23623334
Endotoxemia phenotype 21279327
Fibrosis phenotype 21265825
Glioblastoma disease 30587839
Glioma disease 30587839