1. 药材主信息
| 中文名称: | 凹叶厚朴 |
| 英文名称: | Twolobed Officinal Mangolia |
| 拉丁名称: | Magnolia biloba |
| 使用部位: | bark |
| 功用: | See Magnolia officinalis . |
| 适用症: | See Magnolia officinalis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 26871-46-5 | Isomahanimbine | (+)-Mahanimbicine | 4072580 |
| 20601-85-8 | 四氢厚朴酚 | 2-(2-Hydroxy-5-propylphenyl)-4-propylphenol | 5321851 |
| 28971-03-1 | - | 5,6,7,8-Tetrahydro-4-methylquinoline | 185667 |
| 473-16-5 | - | alpha-Eudesmol | 92762 |
| 125196-77-2 | - | Eudesobovatol A | 442837 |
| 35354-74-6 | 和厚朴酚 | Honokiol | 72303 |
| 87688-90-2 | - | Phenol, 4-(2-propenyl)-2-(4-(2-propenyl)phenoxy)- | 159137 |
| 473-15-4 | β-桉叶醇 | β-Eudesmol | 91457 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADAMTS4 | ADAMTS-2; ADAMTS-4; ADMP-1 | 1q23.3 | 29649568 |
| ADAMTS5 | ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2 | 21q21.3 | 29649568 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26454217 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27940017 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30587839 |
| BAX | BCL2L4 | 19q13.33 | 22259050 |
| BAX | BCL2L4 | 19q13.33 | 29649568 |
| BAX | BCL2L4 | 19q13.33 | 30587839 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30587839 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 29180609 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 21279327 |
| Brain Neoplasms | group | 22259050 |
| Cardiomegaly | phenotype | 25871545 |
| Endotoxemia | phenotype | 21279327 |
| Fibrosis | phenotype | 21265825 |
| Glioblastoma | disease | 30587839 |
| Glioma | disease | 30587839 |
| Head and Neck Neoplasms | group | 29180609 |
| Inflammation | phenotype | 22429472 |
| Inflammation | phenotype | 21279327 |
