1. 药材主信息
| 中文名称: | 苍术 |
| 英文名称: | Rhizome of Swordlike Atractylodes |
| 拉丁名称: | Rhizoma Atractylodis |
| 使用部位: | rhizome |
| 功用: | To remove damp and invigorate the function of the spleen, to disple wind-cold, and to improve eyesight. |
| 适用症: | Spleen-stomach damp turbidity, fatigue hypodynamia, glomus in chest, abdominal distention, inappetence, vomiting and diarrhea, phlegm-rheum, damp edema, exterior damp, heavy head and generalized pain, damp impediment, aching pain in limbs, crippling wilt, night blindness. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 515-69-5 | - | (+)-Epi-alpha-bisabolol | 1201551 |
| 19912-83-5 | - | (-)-alpha-Chamigrene | 442351 |
| 18829-70-4 | (-)-儿茶素 | (-)-Catechin | 73160 |
| 53625-18-6 | - | (-)-Maalioxide | 12085452 |
| 489-29-2 | - | (1aR,3aS,7bS)-1,1,3a,7-Tetramethyl-1a,2,3,3a,4,5,6,7b-octahydro-1H-cyclopropa[a]naphthalene | 101596917 |
| 61642-89-5 | 苍术素醇 | (2E,8E)-9-(Furan-2-yl)nona-2,8-dien-4,6-diyn-1-ol | 10012964 |
| 489-86-1 | - | 2-[(3r,5s,8r)-3,8-Dimethyl-1,2,3,4,5,6,7,8-octahydroazulen-5-yl]propan-2-ol | 72607 |
| 132-37-6 | 芍药素3,5-二-O-葡糖苷氯化物 | 3,5-Bis(beta-D-glucopyranosyloxy)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-benzopyrylium chloride | 159514 |
| 387-80-4 | - | 5beta-Stigmastan-3beta-ol, (24S)- | 6451614 |
| 1110-58-3 | - | 7-(8-Formyl-1,7-dihydroxy-5-isopropyl-6-methoxy-3-methyl-2-naphthyl)-2,8-dihydroxy-4-isopropyl-3-methoxy-6-methyl-naphthalene-1-carbaldehyde | 375713 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADAMTS4 | ADAMTS-2; ADAMTS-4; ADMP-1 | 1q23.3 | 28237856 |
| ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | 3q27.3 | 23623334 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28732574 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26931119 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31406198 |
| BAX | BCL2L4 | 19q13.33 | 23955116 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 23955116 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 23195034 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 23955116 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body Weight | phenotype | 23623334 |
| Cardiomyopathies | group | 31064352 |
| Colorectal Neoplasms | group | 24901054 |
| Dyslipidemias | group | 23623334 |
| Encephalitis | disease | 30975172 |
| Hyperalgesia | phenotype | 30975172 |
| Hyperalgesia | phenotype | 29017971 |
| Hyperglycemia | disease | 23623334 |
| Hypersensitivity | group | 25629436 |
| Inflammation | phenotype | 29017971 |
