科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 靶点主信息

NCBI Gene id: 9474
Gene_name: ATG5
Gene alias: APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5
Map location: 6q21
Type of gene: protein-coding
Description: autophagy related 5
OMIM_id: 604261
HGNC_id: 589
Ensembl_id: ENSG00000057663

2. 相关药材

中文名称 英文名称 拉丁文名称
白花蛇舌草 all - grass of Spreading Hedyotis Herba Hedyotis Diffusae
白藜芦醇 White Falsehellebore Veratrum album
白蔹 root of Japanese Ampelopsis Radix Ampelopsis
白屈菜 Chelidonii Herba -
萹蓄 all-grass of common knotgrass Herba Polygoni Avicularis
博落回 Pink Plumepoppy Macleaya cordata
波叶大黄 Rheum undulatum Linn -
柴胡 root of Chinese Thorowax Radix Bupleuri
蟾蜍 Toad Bufo bufo gargarizans, Bufo melanostictus
蟾酥 Toad Skin Secretion Cake Bufo bufo gargarizans, Bufo melanostictus

3. 相关成分

CAS号 中文名称 英文名称 参考文献
6902-77-8 京尼平 Genipin 442424
68406-26-8 - Ginsenoside Rb3 12912363
501-36-0 白藜芦醇 Resveratrol 445154
82-08-6 Rottlerin Rottlerin 5281847
2447-54-3 血根碱 Sanguinarium 5154
62949-76-2 xanthoangelol Xanthoangelol 643007

4. 相关疾病

疾病名称 疾病类型 参考文献
Acute kidney injury disease 21975863
Acute Lung Injury disease 25512625
Adenocarcinoma group 25661734
Adenoma group 26223300
Adenomatous Polyposis Coli disease 24516128
Adrenoleukodystrophy disease 25822341
Aging phenotype 25677910
Aging phenotype 28677234
Aging phenotype 28070015
Aging phenotype 23293221