1. 药材主信息
| 中文名称: | 蟾蜍 |
| 英文名称: | Toad |
| 拉丁名称: | Bufo bufo gargarizans, Bufo melanostictus |
| 使用部位: | whole body |
| 功用: | To resolve toxin and dissipate binds, disperse accumulation and disinhibit water, kill worms and disperse gan . |
| 适用症: | Welling abscess and flat abscess, clove sore, effusion of back, scrofula, malign sore, concretion and accumulation, ascites, edema, child gan accumulation, tetanus, chronic cough and asthma. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 487-93-4 | 蟾蜍色胺 | Bufotenine | 10257 |
| 464-81-3 | - | Bufotoxin | 20054854 |
| 470-37-1 | 华蟾毒精；华蟾蜍精 | Cinobufagin | 11969542 |
| 4064-09-9 | - | Hellebrigenin 3-acetate | 267436 |
| 465-39-4 | 酯蟾毒配基 | Resibufogenin | 6917974 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28492559 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 21763418 |
| ATP1A1 | CMT2DD; HOMGSMR2 | 1p13.1 | 30739221 |
| ATP1A3 | AHC2; ATP1A1; CAPOS; DYT12; RDP | 19q13.2 | 30739221 |
| ATP1A4 | ATP1A1; ATP1AL2 | 1q23.2 | 30739221 |
| BECN1 | ATG6; VPS30; beclin1 | 17q21.31 | 21763418 |
| CYP11B2 | ALDOS; CPN2; CYP11B; CYP11BL; CYPXIB2; P-450C18; P450C18; P450aldo | 8q24.3 | 21913902 |
| DDX58 | RIG-I; RIG1; RIGI; RLR-1; SGMRT2 | 9p21.1 | 21076398 |
| DNAH8 | ATPase; hdhc9 | 6p21.2 | 21076398 |
| GUCY2C | DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR | 12p12.3 | 21913902 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Autoimmune Diseases | group | 21076398 |
| Colonic Neoplasms | group | 21763418 |
| Glioma | disease | 30739221 |
| Multiple Myeloma | disease | 28492559 |
