1. 药材主信息
| 中文名称: | 博落回 |
| 英文名称: | Pink Plumepoppy |
| 拉丁名称: | Macleaya cordata |
| 使用部位: | whole herb with root |
| 功用: | To dispel wind, dissipate stasis, resolve toxin, relieve pain, kill worms. |
| 适用症: | Ulcer of uterine cervix, carcinoma of uterine cervix, carcinoma of thyroid, swollen welling abscess and clove sores, ulcer of lower limb, hemorrhoids, eczema, snake or insect bites, painful swelling from knocks and falls, pain in joints due to rheumatalgia, decayed toothache, intractable lichen, trichomoniasis, brandy nose. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 24240-04-8 | 别隐品碱 | Allocryptopine | 98570 |
| 32906-88-0 | 博落回醇碱 | Bocconoline | 181121 |
| 478-03-5 | - | Chelerythrine hydroxide | 5351594 |
| 548-30-1 | 氧化血根碱 | Hydroxysanguinarine | 443716 |
| 10176-66-6 | 石吊兰素 | Nevadensin | 160921 |
| 2447-54-3 | 血根碱 | Sanguinarium | 5154 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27154977 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31819036 |
| ASAH1 | AC; ACDase; ASAH; PHP; PHP32; SMAPME | 8p22 | 30735839 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 26472194 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 31163195 |
| BECN1 | ATG6; VPS30; beclin1 | 17q21.31 | 28288416 |
| CCND1 | BCL1; D11S287E; PRAD1; U21B31 | 11q13.3 | 31163195 |
| EIF4A1 | DDX2A; EIF-4A; EIF4A; eIF-4A-I; eIF4A-I | 17p13.1 | 31402318 |
| GSK3B | - | 3q13.33 | 27154977 |
| HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | 14q23.2 | 31819036 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 26472194 |
| Glioma | disease | 26472194 |
| leukemia | disease | 27154977 |
| Liver neoplasms | group | 31163195 |
| Lung Neoplasms | group | 28288416 |
| Prostatic Neoplasms | group | 30735839 |
