1. 靶点主信息
NCBI Gene id: | 2879 |
Gene_name: | GPX4 |
Gene alias: | GPx-4; GSHPx-4; MCSP; PHGPx; SMDS; snGPx; snPHGPx |
Map location: | 19p13.3 |
Type of gene: | protein-coding |
Description: | glutathione peroxidase 4 |
OMIM_id: | 138322 |
HGNC_id: | 4556 |
Ensembl_id: | ENSG00000167468 |
2. 相关药材
中文名称 | 英文名称 | 拉丁文名称 |
百部 | Root of Japanese Stemo | Radix Stemoe |
白藜芦醇 | White Falsehellebore | Veratrum album |
白鲜皮 | Densefruit Pittany Root-bark Equivalent plant: Dic | Dictamnus dasycarpus |
白鲜皮 | Dictamni Cortex | - |
半夏 | tuber of Pinellia | Rhizoma Pinelliae |
赤小豆 | Rice Bean | Semen Phaseoli |
穿破石 | root of Tricuspid cudrania | Radix Cudraniae |
催眠睡茄 | Somniferous Withania | Withania somnifera |
大腹皮 | Areca Catechu L. | - |
大黄 | root and rhziome of Sorrel Rhubarb | Radix et Rhizoma Rhei |
3. 相关成分
CAS号 | 中文名称 | 英文名称 | 参考文献 |
501-36-0 | 白藜芦醇 | Resveratrol | 445154 |
535-83-1 | 葫芦巴碱 | Trigonelline | 5570 |
5119-48-2 | 醉茄素A | Withaferin A | 265237 |
4. 相关疾病
疾病名称 | 疾病类型 | 参考文献 |
Acute kidney injury | disease | 21975863 |
Acute Lung Injury | disease | 25512625 |
Adenoma | group | 26223300 |
Adenomatous Polyposis Coli | disease | 24516128 |
Adrenoleukodystrophy | disease | 25822341 |
Aging | phenotype | 25677910 |
Aging | phenotype | 28677234 |
Aging | phenotype | 28070015 |
Aging | phenotype | 23293221 |
Aging | phenotype | 22304913 |