1. 成分信息
| 英文名: | Withaferin A |
| 中文名: | 醉茄素A |
| CAS编号: | 5119-48-2 |
| 分子式: | C28H38O6 |
| 分子量: | 470.6 |
| SMILES: | CC1=C(C(=O)OC(C1)C(C)C2CCC3C2(CCC4C3CC5C6(C4(C(=O)C=CC6O)C)O5)C)CO |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 催眠睡茄 | Somniferous Withania | Withania somnifera |
| 南鹤虱 | Fructus Carotae | - |
| 山豆根 | Vietmese Sophora Root | Radix Sophorae Tonkinensis |
| 水茄 | Water Nightshade | Solanum torvum |
| 洋金花 | Datura Flower | Flos Daturae |
3. 相关靶点
| 基因靶点 | 靶点位置 | 参考文献 |
| ACP5 | 19p13.2 | 23969857 |
| AK4 | 1p31.3 | 30696468 |
| AKT1 | 14q32.33 | 25444914 |
| AKT1 | 14q32.33 | 26913603 |
| AKT1 | 14q32.33 | 28919038 |
| ATF3 | 1q32.3 | 31642559 |
| ATF4 | 22q13.1 | 31642559 |
| BAX | 19q13.33 | 27250656 |
| BCL2 | 18q21.33 | 27250656 |
| BCL2L11 | 2q13 | 31642559 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Amyotrophic Lateral Sclerosis | disease | 25404049 |
| Amyotrophic Lateral Sclerosis | disease | 22084410 |
| Diabetes | disease | 23969857 |
| Glioblastoma | disease | 31642559 |
| Gliosis | phenotype | 27685630 |
| Glucose tolerance test | phenotype | 23318585 |
| Inflammation | phenotype | 27250656 |
| Inflammation | phenotype | 23318585 |
| Kidney Diseases | group | 27250656 |
| Liver neoplasms | group | 30696468 |
