科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 穿破石
英文名称: root of Tricuspid cudrania
拉丁名称: Radix Cudraniae
使用部位: -
功用: 1. To remove blood stasis, alleviate pain, expel wind and dampness. For rheumatism and trauma. Recently , also for acute and chronic hepatitis, tumour of digestive tract, carcinoma of liver, pancreas and lung, etc .2. To relieve cough and eliminate sputum. For productive cough.
适用症: 1. To remove blood stasis, alleviate pain, expel wind and dampness. For rheumatism and trauma. Recently , also for acute and chronic hepatitis, tumour of digestive tract, carcinoma of liver, pancreas and lung, etc .2. To relieve cough and eliminate sputum
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
111-87-5 1-辛醇 1-Octanol 957
87-44-5 β-石竹烯 Caryophyllene 5281515
63596-94-1 - Cudranone 191694
630-01-3 二十六烷 Hexacosane 12407
126-91-0 (R)-3,7-二甲基-1,6-辛二烯-3-醇 Linalool, (-)- 443158
480-16-0 桑色素 Morin 5281670
141-12-8 橙花醇乙酸酯 Neryl acetate 1549025
29700-22-9 氧化白藜芦醇 Oxyresveratrol 5281717
57-10-3 棕榈酸 Palmitic Acid 985
501-36-0 白藜芦醇 Resveratrol 445154

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 7q21.12 22011009
Abcb1b Abcb1; Mdr1; Mdr1b; Pgy-1; Pgy1; mdr 5 A1|5 3.43 cM 22011009
ACE2 ACEH Xp22.2 28935757
ACTA2 ACTSA 10q23.31 26891034
ACTG2 ACT; ACTA3; ACTE; ACTL3; ACTSG; VSCM 2p13.1 23262250
ADIPOQ ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 3q27.3 22388319
AGT ANHU; SERPINA8; hFLT1 1q42.2 29566148
AHR RP85; bHLHe76 7p21.1 24247421
AHR RP85; bHLHe76 7p21.1 31027257
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 20720562

4. 相关疾病

疾病名称 疾病类型 参考文献
Acute kidney injury disease 21975863
Acute Lung Injury disease 25512625
Adenoma group 26223300
Adenomatous Polyposis Coli disease 24516128
Adrenoleukodystrophy disease 25822341
Aging phenotype 25677910
Aging phenotype 28677234
Aging phenotype 28070015
Aging phenotype 23293221
Aging phenotype 22304913