1. 成分信息
| 英文名: | Tauroursodeoxycholic acid |
| 中文名: | 牛磺熊去氧胆酸 |
| CAS编号: | 14605-22-2 |
| 分子式: | C26H45NO6S |
| 分子量: | 499.7 |
| SMILES: | CC(CCC(=O)NCCS(=O)(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 熊胆 | Bear Gall | Selenarctos thibetanus, Ursus arctos |
3. 相关靶点
| 基因靶点 | 靶点位置 | 参考文献 |
| ABCB1 | 7q21.12 | 28688954 |
| ABCB11 | 2q31.1 | 28688954 |
| ABCC2 | 10q24.2 | 28688954 |
| AKT1 | 14q32.33 | 25407160 |
| ATF4 | 22q13.1 | 28688954 |
| ATF6 | 1q23.3 | 24225943 |
| ATF6 | 1q23.3 | 31045581 |
| ATXN1 | 6p22.3 | 25407160 |
| CASP1 | 11q22.3 | 27706903 |
| CCN2 | 6q23.2 | 22974733 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aortic Diseases | group | 24379182 |
| Aortic Valve Stenosis | disease | 23928865 |
| Blood Pressure | phenotype | 24379182 |
| Blood Pressure | phenotype | 23288166 |
| Blood Pressure | phenotype | 21035453 |
| Brucellosis | disease | 24339776 |
| Calcinosis | phenotype | 23928865 |
| Carcinogenesis | phenotype | 25695629 |
| Cardiovascular Diseases | group | 27503949 |
| Chemical and Drug Induced Liver Injury | disease | 27706903 |
