1. 药材主信息
| 中文名称: | 熊胆 |
| 英文名称: | Bear Gall |
| 拉丁名称: | Selenarctos thibetanus, Ursus arctos |
| 使用部位: | gall bladder |
| 功用: | To clear heat and resolve toxin, calm liver and brighten eyes, stanch bleeding and kill worms. |
| 适用症: | Fright wind, epilepsy, convulsion due to liver heat and liver wind, swollen pain in red eyes due to liver heat, aversion to light, eye screen, swelling pain of welling abscess and sore, swelling pain from hemorrhoids. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 51-84-3 | - | Acetylcholine | 187 |
| 474-25-9 | 鹅去氧胆酸 | Chenodiol | 10133 |
| 81-25-4 | 胆酸 | Cholic acid | 221493 |
| 62-49-7 | 2-羟基-N,N,N-三甲基乙铵 | Choline | 305 |
| 64-85-7 | 去氧皮质酮 | Desoxycortone | 6166 |
| 81-24-3 | 牛磺胆酸 | Taurocholic acid | 6675 |
| 516-50-7 | - | Taurodeoxycholic Acid | 2733768 |
| 14605-22-2 | 牛磺熊去氧胆酸 | Tauroursodeoxycholic acid | 9848818 |
| 14605-22-2 | 牛磺熊去氧胆酸 | Tauroursodeoxycholic acid | 9848818 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 28688954 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 21649640 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 28688954 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 28688954 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25407160 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| AREG | AR; AREGB; CRDGF; SDGF | 4q13.3 | 24520077 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Aortic Diseases | group | 24379182 |
| Aortic Valve Stenosis | disease | 23928865 |
| Blood Pressure | phenotype | 24379182 |
| Blood Pressure | phenotype | 23288166 |
| Blood Pressure | phenotype | 21035453 |
| Brucellosis | disease | 24339776 |
| Calcinosis | phenotype | 23928865 |
| Carcinogenesis | phenotype | 25695629 |
