1. 靶点主信息
| NCBI Gene id: | 834 |
| Gene_name: | CASP1 |
| Gene alias: | ICE; IL1BC; P45 |
| Map location: | 11q22.3 |
| Type of gene: | protein-coding |
| Description: | caspase 1 |
| OMIM_id: | 147678 |
| HGNC_id: | 1499 |
| Ensembl_id: | ENSG00000137752 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 凹叶厚朴 | Twolobed Officinal Mangolia | Magnolia biloba |
| 八角茴香 | Chinese Star Anise | Fructus Anisi Stellati |
| 百合 | Bulb of Greenish Lily | Bulbus Lilii |
| 百合花 | Flos Lilii brownii | - |
| 百合子 | Semen Lilii brownii | - |
| 白蔹 | root of Japanese Ampelopsis | Radix Ampelopsis |
| 白屈菜 | Chelidonii Herba | - |
| 白头翁 | Root of Chinese Pulsatilla | Radix Pulsatillae |
| 瓣蕊唐松草 | Petalformed Meadowrue | Thalictrum petaloideum |
| 草贝母 | Indian Iphigenia | Iphigenia indica |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 64-86-8 | 秋水仙碱 | Colchicine | 6167 |
| 3486-66-6 | 黄连碱 | Coptisine | 72322 |
| 2050-87-5 | 大蒜素 | Diallyl trisulfide | 16315 |
| 989-51-5 | 表没食子儿茶素没食子酸酯 | Epigallocatechin Gallate | 65064 |
| 35354-74-6 | 和厚朴酚 | Honokiol | 72303 |
| 478-43-3 | 大黄酸 | Rhein | 10168 |
| 14605-22-2 | 牛磺熊去氧胆酸 | Tauroursodeoxycholic acid | 9848818 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acne Vulgaris | disease | 22763784 |
| Acute Coronary Syndrome | disease | 23265346 |
| Acute Coronary Syndrome | disease | 29055633 |
| Acute Coronary Syndrome | disease | 27129183 |
| Acute Lung Injury | disease | 21279327 |
| Alzheimer's Disease | disease | 22300765 |
| Angina Pectoris | phenotype | 31733140 |
| Anti-Glomerular Basement Membrane Disease | disease | 21544063 |
| Aortic Diseases | group | 24379182 |
| Aortic Valve Stenosis | disease | 23928865 |
