1. 靶点主信息
| NCBI Gene id: | 468 |
| Gene_name: | ATF4 |
| Gene alias: | CREB-2; CREB2; TAXREB67; TXREB |
| Map location: | 22q13.1 |
| Type of gene: | protein-coding |
| Description: | activating transcription factor 4 |
| OMIM_id: | 604064 |
| HGNC_id: | 786 |
| Ensembl_id: | ENSG00000128272 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 白花菜子 | Semen Cleomis | - |
| 白毛夏枯草 | all - grass of Decumbent Bugle | Herha Ajugae Ciliatae |
| 绒叶含笑 | Longhairy Michelia | Michelia lanuginosa |
| 长叶天名精 | Longleaf Carpesium | Carpesium longifolium |
| 朝鲜当归 | Gigantic Angelica | Angelica gigas |
| 催眠睡茄 | Somniferous Withania | Withania somnifera |
| 玳玳花 | Citrus Aurantium | - |
| 刀豆 | Jack Bean | Semen Cavaliae |
| 东北蛔蒿 | Northeast Seriphidium | Seriphidium finitum [Syn. Artemisia finita] |
| 儿茶 | Cutch, Black Catechu | Catechu |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 528-48-3 | 漆黄素 | Fisetin | 5281614 |
| 537-42-8 | 紫檀芪 | Pterostilbene | 5281727 |
| 14605-22-2 | 牛磺熊去氧胆酸 | Tauroursodeoxycholic acid | 9848818 |
| 5119-48-2 | 醉茄素A | Withaferin A | 265237 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 21719790 |
| Amyotrophic Lateral Sclerosis | disease | 25404049 |
| Amyotrophic Lateral Sclerosis | disease | 22084410 |
| Aortic Diseases | group | 24379182 |
| Aortic Valve Stenosis | disease | 23928865 |
| Blood Pressure | phenotype | 21321301 |
| Blood Pressure | phenotype | 24379182 |
| Blood Pressure | phenotype | 23288166 |
| Blood Pressure | phenotype | 21035453 |
| Bone neoplasms | group | 28965856 |