1. 靶点主信息
| NCBI Gene id: | 8837 |
| Gene_name: | CFLAR |
| Gene alias: | CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; cFLIP |
| Map location: | 2q33.1 |
| Type of gene: | protein-coding |
| Description: | CASP8 and FADD like apoptosis regulator |
| OMIM_id: | 603599 |
| HGNC_id: | 1876 |
| Ensembl_id: | ENSG00000003402 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 白附子 | rhizome of Giant Typhonium | Rhizoma Typhonii |
| 白花蛇舌草 | all - grass of Spreading Hedyotis | Herba Hedyotis Diffusae |
| 败酱草 | All - grass of Dahurian Patrinia | Herba Patriniae |
| 白木香 | Chinese Eaglewood | Aquilaria sinensis |
| 白头翁 | Root of Chinese Pulsatilla | Radix Pulsatillae |
| 半枝莲 | all - grass of Barbed Skullcap | Herba Scutellariae barbatae |
| 秘鲁钩藤 | Una de Gato (Cat’s Claw) | Uncaria tomentosa |
| 薄荷 | Mentha, Peppermint | herba Menthae |
| 绒叶含笑 | Longhairy Michelia | Michelia lanuginosa |
| 长叶天名精 | Longleaf Carpesium | Carpesium longifolium |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 84573-16-0 | Rocaglamide | Rocaglamide | 331783 |
| 83-79-4 | 鱼藤酮 | Rotenone | 6758 |
| 38748-32-2 | 雷公藤甲素 | Triptolide | 107985 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 21719790 |
| Alzheimer's Disease | disease | 22229260 |
| Blood Pressure | phenotype | 21321301 |
| Body Weight | phenotype | 22220673 |
| Bone neoplasms | group | 28965856 |
| Bone neoplasms | group | 29096654 |
| Cancer Pain | phenotype | 29096654 |
| Carcinoma | group | 25553117 |
| Carcinoma, Pancreatic Ductal | disease | 27384421 |
| Carcinoma, Pancreatic Ductal | disease | 26597727 |
