1. 成分信息
| 英文名: | Triptolide |
| 中文名: | 雷公藤甲素 |
| CAS编号: | 38748-32-2 |
| 分子式: | C20H24O6 |
| 分子量: | 360.4 |
| SMILES: | CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 火麻仁 | Hemp Seed | Semen Canbis;Fructus Canbis |
| 昆明山海棠 | Glaucousback Threewingnut | Tripterygium hypoglaucum |
| 雷公藤 | root of common htreewingnut | radix tripterygii wilfordii |
| 紫槿皮 | - | - |
3. 相关靶点
| 基因靶点 | 靶点位置 | 参考文献 |
| ABCG2 | 4q22.1 | 26597727 |
| AKR1B1 | 7q33 | 28638477 |
| AKT1 | 14q32.33 | 29246323 |
| BCL2L11 | 2q13 | 29523159 |
| BIRC5 | 17q25.3 | 23499892 |
| CASP3 | 4q35.1 | 23758884 |
| CASP3 | 4q35.1 | 24309928 |
| CASP3 | 4q35.1 | 25229559 |
| CASP8 | 2q33.1 | 24662747 |
| CASP8 | 2q33.1 | 25229559 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body Weight | phenotype | 22220673 |
| Bone neoplasms | group | 29096654 |
| Cancer Pain | phenotype | 29096654 |
| Carcinoma, Pancreatic Ductal | disease | 27384421 |
| Carcinoma, Pancreatic Ductal | disease | 26597727 |
| Chronic pain | phenotype | 28300618 |
| Colonic Neoplasms | group | 23758884 |
| Colorectal Neoplasms | group | 31122284 |
| Diabetes Mellitus, Experimental | disease | 30741721 |
| Diabetes Mellitus, Experimental | disease | 23530831 |
