1. 药材主信息
| 中文名称: | 白头翁 |
| 英文名称: | Root of Chinese Pulsatilla |
| 拉丁名称: | Radix Pulsatillae |
| 使用部位: | root |
| 功用: | 1. To clear heat and release toxins; 2. To cool the blood and stop dysentery |
| 适用症: | Amebic dysentery, nosebleed, flooding and spotting, bleeding from hemorrhoids, cold-heat warm malaria, vaginal discharge, pudendal itch, eczema, scrofula, welling abscess, painful red eyes, neurodermatitis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 129724-84-1 | 白头翁皂苷A3 | Anemoside A3 | 11721847 |
| 20307-14-6 | - | (2R,3R,5S,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(1H-indol-3-yloxy)oxan-4-one | 101529308 |
| 7471-58-1 | 3-(氯甲基)-6-(三氟甲基)吡啶 | 2(1H)-Quinazolinone | 344381 |
| 1333-47-7 | - | 3-Methylcoumarin | 17130 |
| 4339-72-4 | 齐敦果酸乙酸酯 | 3-O-Acetyloleanolic acid | 151202 |
| 55085-47-7 | 5,6,7-三甲氧基香豆素 | 5,6,7-Trimethoxycoumarin | 148724 |
| 27013-91-8 | α-常春藤皂苷 | alpha-Hederin | 73296 |
| 90921-11-2 | 白头翁素 | Anemonin | 10496 |
| 38216-54-5 | Aureusidin | Aureusidin | 5281220 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AHR | RP85; bHLHe76 | 7p21.1 | 22533375 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Coronary Syndrome | disease | 23265346 |
| Acute Coronary Syndrome | disease | 29055633 |
| Acute Coronary Syndrome | disease | 27129183 |
| Angina Pectoris | phenotype | 31733140 |
| Atrial Fibrillation | disease | 25172965 |
| Atrial Fibrillation | disease | 22090167 |
| Atrial Fibrillation | disease | 24508207 |
| Atrial Fibrillation | disease | 23040570 |
| Behcet Syndrome | disease | 22632542 |
| Blood Pressure | phenotype | 25076013 |
