1. 成分信息
| 英文名: | Rotenone |
| 中文名: | 鱼藤酮 |
| CAS编号: | 83-79-4 |
| 分子式: | C23H22O6 |
| 分子量: | 394.4 |
| SMILES: | CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 地瓜子 | Wayaka Yambean Seed | Pachyrhizus erosus |
| 豆薯 | Wayaka Yambean | Pachyrrhizus erosus |
| 灰叶根 | Purple Tephrosia Root | Tephrosia purpurea |
| 鸡血藤根 | Leatherleaf Millettia Root | Millettia reticulata |
| 苦檀子 | Thickfruit Millettia | Millettia pachycarpa |
| 毛蕊花 | Flannel Mullein | Verbascum thapsus |
| 毛鱼藤 | Tubaroot Jewelvine | Derris elliptica |
| 鱼藤 | Trifoliate Jewelvine | Derris trifoliata |
3. 相关靶点
| 基因靶点 | 靶点位置 | 参考文献 |
| APP | 21q21.3 | 22229260 |
| BCL2L1 | 20q11.21 | 25522273 |
| CAMK2A | 5q32 | 22526376 |
| CASP3 | 4q35.1 | 22526376 |
| CFLAR | 2q33.1 | 25522273 |
| CNTNAP1 | 17q21.2 | 23816754 |
| MB | 22q12.3 | 21742033 |
| NDUFS4 | 5q11.2 | 21383081 |
| NDUFV1 | 11q13.2 | 22244441 |
| NDUFV1 | 11q13.2 | 25452141 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 22229260 |
| Demyelinating Diseases | group | 23816754 |
| Hyperalgesia | phenotype | 22244441 |
| Lung Neoplasms | group | 25522273 |
| Nerve Degeneration | phenotype | 21742033 |
| Nerve Degeneration | phenotype | 21383081 |
| Neuralgia | phenotype | 22244441 |
| Neurotoxicity Syndromes | group | 21742033 |
| Parkinson Disease | disease | 21383081 |
