科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 靶点主信息

NCBI Gene id: 6331
Gene_name: SCN5A
Gene alias: CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1
Map location: 3p22.2
Type of gene: protein-coding
Description: sodium voltage-gated channel alpha subunit 5
OMIM_id: 600163
HGNC_id: 10593
Ensembl_id: ENSG00000183873

2. 相关药材

中文名称 英文名称 拉丁文名称
白藜芦醇 White Falsehellebore Veratrum album
半边莲 Chinese Lobelia Herb Herba Lobeliae Chinensis
赤小豆 Rice Bean Semen Phaseoli
穿破石 root of Tricuspid cudrania Radix Cudraniae
钝叶车轴草 Suckling Clover Trifolium dubium
防己 Root of Fourstamen Stephania Radix Stephaniae Tetrandrae
防己叶菝葜 Gansu Greenbrier Smilax menispermoidea
甘遂 root of Gansui Radix Kansui
枸骨叶 Folium Ilicis Cornutae -
构树 Common Papermulberry Broussonetia papyrifera

3. 相关成分

CAS号 中文名称 英文名称 参考文献
4368-28-9 - (1R,5R,6R,7R,9S,11S,13S,14R)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-ene-5,9,12,13,14-pentol 139251219
520-33-2 橙皮素 Hesperetin 72281
501-36-0 白藜芦醇 Resveratrol 445154

4. 相关疾病

疾病名称 疾病类型 参考文献
Acute kidney injury disease 21975863
Acute Lung Injury disease 25512625
Adenoma group 26223300
Adenomatous Polyposis Coli disease 24516128
Adrenoleukodystrophy disease 25822341
Aging phenotype 25677910
Aging phenotype 28677234
Aging phenotype 28070015
Aging phenotype 23293221
Aging phenotype 22304913