1. 药材主信息
| 中文名称: | 甘遂 |
| 英文名称: | root of Gansui |
| 拉丁名称: | Radix Kansui |
| 使用部位: | tuberoid |
| 功用: | To cause drastic purgation and expel the retained water. |
| 适用症: | Edema, ascites, flowing rheum in chest, concretion conglomeration accumulation and gathering, epilepsy, cough and asthma, urinar y and fecal stoppage. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 67-47-0 | 5-羟甲基糠醛 | 5-Hydroxymethylfurfural | 237332 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 133898-77-8 | Kansuiphorin C | CID 102004601 | 102004601 |
| 77-92-9 | 无水柠檬酸 | Citric Acid | 311 |
| 514-47-6 | 大戟二烯醇 | Euphol | 441678 |
| 566-14-3 | 大戟醇 | Euphorbadienol | 10863111 |
| 35897-99-5 | 千金子素 | Euphorbetin | 5317297 |
| 70469-59-9 | - | Euponin | 5281465 |
| 52286-59-6 | 人参皂苷Re | Ginsenoside B2 | 441921 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 22011009 |
| Abcb1b | Abcb1; Mdr1; Mdr1b; Pgy-1; Pgy1; mdr | 5 A1|5 3.43 cM | 22011009 |
| ACE2 | ACEH | Xp22.2 | 28935757 |
| ACTA2 | ACTSA | 10q23.31 | 26891034 |
| ACTG2 | ACT; ACTA3; ACTE; ACTL3; ACTSG; VSCM | 2p13.1 | 23262250 |
| ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | 3q27.3 | 22388319 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 29566148 |
| AHR | RP85; bHLHe76 | 7p21.1 | 24247421 |
| AHR | RP85; bHLHe76 | 7p21.1 | 31027257 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20720562 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Abdominal Pain | phenotype | 28164346 |
| Acute kidney injury | disease | 21975863 |
| Acute Lung Injury | disease | 25512625 |
| Adenoma | group | 26223300 |
| Adenomatous Polyposis Coli | disease | 24516128 |
| Adrenoleukodystrophy | disease | 25822341 |
| Aging | phenotype | 25677910 |
| Aging | phenotype | 28677234 |
| Aging | phenotype | 28070015 |
| Aging | phenotype | 23293221 |
