1. 靶点主信息
| NCBI Gene id: | 6093 |
| Gene_name: | ROCK1 |
| Gene alias: | P160ROCK; ROCK-I |
| Map location: | 18q11.1 |
| Type of gene: | protein-coding |
| Description: | Rho associated coiled-coil containing protein kinase 1 |
| OMIM_id: | 601702 |
| HGNC_id: | 10251 |
| Ensembl_id: | ENSG00000067900 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 白钩藤 | White Gambirplant | Uncaria sessilifructus [Syn. Nauclea sessilifructu |
| 秘鲁钩藤 | Una de Gato (Cat’s Claw) | Uncaria tomentosa |
| 冬瓜皮 | Chinese Waxgourd Peel | Exocarpium Benincasae |
| 杜仲叶 | Eucommiae Folium | - |
| 多买钩藤 | Many-veined Gambirplant | Uncaria nervosa |
| 风箱树叶 | Common Butterbush | Cephalanthus occidentalis |
| 钩藤 | Gambir Plant | Ramulus Uncariae cum Uncis |
| 圭亚那钩藤 | Garabato,Unganangi, Cat’s Claw | Uncaria guianensis |
| 蝴蝶花 | Fringed Iris | Iris japonica |
| 华钩藤 | Chinese Gambirplant | Uncaria sinensis |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7729-23-9 | 毛钩藤碱 | Hirsutine | 3037884 |
| 38748-32-2 | 雷公藤甲素 | Triptolide | 107985 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body Weight | phenotype | 22220673 |
| Bone neoplasms | group | 29096654 |
| Cancer Pain | phenotype | 29096654 |
| Carcinoma, Pancreatic Ductal | disease | 27384421 |
| Carcinoma, Pancreatic Ductal | disease | 26597727 |
| Chronic pain | phenotype | 28300618 |
| Colonic Neoplasms | group | 23758884 |
| Colorectal Neoplasms | group | 31122284 |
| Cytomegalovirus Infections | group | 27336364 |
| Diabetes Mellitus, Experimental | disease | 30741721 |
