1. 药材主信息
| 中文名称: | 钩藤 |
| 英文名称: | Gambir Plant |
| 拉丁名称: | Ramulus Uncariae cum Uncis |
| 使用部位: | hooked stem-branch |
| 功用: | To remove heat, subdue hyperactivity of the liver, and arrest convulsions. |
| 适用症: | Infant fright wind and night crying, exuberant heat stirring wind, epilepsy of pregnancy, liver yang dizziness, liver fire headache. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 35323-91-2 | - | (+)-Epicatechin | 182232 |
| 79595-97-4 | - | (2S,3R,4R,4aS,10bR)-3,4,8,9,10-pentahydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one | 73192 |
| 23513-08-8 | 8-姜酚 | (8)-Gingerol | 168114 |
| 483-34-1 | 四氢非洲防己碱 | (S)-Tetrahydrocolumbamine | 440229 |
| 32899-41-5 | L-ALPHA-PALMITIN | 1-Hexadecanoyl-sn-glycerol | 3084463 |
| 54483-84-0 | 3a-二氢卡丹宾 | 3-Dihydrocadambine | 162138 |
| 62014-69-1 | - | 3beta-Isodihydrocadambine | 188431 |
| 482-39-3 | 阿福豆苷 | Afzelin | 5316673 |
| 642-17-1 | 阿枯米精 | Akuammigine | 1268096 |
| 40217-50-3 | - | Angustidine | 3084770 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | 10q25.2 | 22188400 |
| ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | 10q25.2 | 22311903 |
| ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | 10q25.2 | 22836250 |
| ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | 10q25.2 | 25298321 |
| ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | 10q25.2 | 25572945 |
| ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | 10q25.2 | 27273730 |
| ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | 10q25.2 | 27659409 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29789524 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27017346 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Anxiety | disease | 28726252 |
| Anxiety Disorders | group | 24237691 |
| Atherosclerosis | disease | 27017346 |
| Blood Pressure | phenotype | 22311903 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Cardiomegaly | phenotype | 27659409 |
| Cognition Disorders | group | 21708244 |
| Colitis | disease | 25281414 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
