1. 药材主信息
| 中文名称: | 华钩藤 |
| 英文名称: | Chinese Gambirplant |
| 拉丁名称: | Uncaria sinensis |
| 使用部位: | hooked stem-branch |
| 功用: | See Uncaria rhynchophylla. |
| 适用症: | See Uncaria rhynchophylla. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 54483-84-0 | 3a-二氢卡丹宾 | 3-Dihydrocadambine | 162138 |
| 62014-69-1 | - | 3beta-Isodihydrocadambine | 188431 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
| 630-94-4 | 去氢钩藤碱 | Corynoxeine | 44568160 |
| 7729-23-9 | 毛钩藤碱 | Hirsutine | 3037884 |
| 51014-29-0 | 异去氢钩藤碱 | Isocorynoxeine | 3037448 |
| 5171-37-9 | 钩藤碱E | Isopteropodine | 9885603 |
| 6859-01-4 | 异钩藤碱 | Isorhynchophylline | 3037048 |
| 6859-01-4 | 异钩藤碱 | Isorhynchophylline | 3037048 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29789524 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22832932 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 27472952 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body Weight | phenotype | 24559844 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Inflammation | phenotype | 21708244 |
| leukemia | disease | 23584398 |
| leukemia | disease | 21950524 |
| Liver Cirrhosis, Experimental | disease | 21168456 |
| Liver neoplasms | group | 27036874 |
