1. 靶点主信息
| NCBI Gene id: | 4170 |
| Gene_name: | MCL1 |
| Gene alias: | BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT |
| Map location: | 1q21.2 |
| Type of gene: | protein-coding |
| Description: | MCL1 apoptosis regulator, BCL2 family member |
| OMIM_id: | 159552 |
| HGNC_id: | 6943 |
| Ensembl_id: | ENSG00000143384 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 艾叶 | leaf of Argy Wormwood | Folium Artemisiae Argyi |
| 百部 | Root of Japanese Stemo | Radix Stemoe |
| 白鲳 | Drug Sweetflag | Acorus calamus |
| 白附子 | rhizome of Giant Typhonium | Rhizoma Typhonii |
| 白果叶 | Ginkgo Leaf | Ginkgo biloba |
| 百合 | Bulb of Greenish Lily | Bulbus Lilii |
| 白花蛇舌草 | all - grass of Spreading Hedyotis | Herba Hedyotis Diffusae |
| 败酱草 | All - grass of Dahurian Patrinia | Herba Patriniae |
| 白藜芦醇 | White Falsehellebore | Veratrum album |
| 百里香 | Breckland Thyme | Thymus serpyllum |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 469-83-0 | 咖啡醇 | Cafestol | 108052 |
| 34157-83-0 | 雷公藤红素 | Celastrol | 122724 |
| 458-37-7 | 姜黄素 | Curcumin | 969516 |
| 4449-51-8 | 环巴胺 | Cyclopamine | 442972 |
| 33069-62-4 | 紫杉醇 | Paclitaxel | 36314 |
| 520-12-7 | 柳穿鱼黄素 | Pectolinarigenin | 5320438 |
| 482-44-0 | 欧前胡素 | Pentosalen | 10212 |
| 130-86-9 | 原阿片碱 | Protopine | 4970 |
| 501-36-0 | 白藜芦醇 | Resveratrol | 445154 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 31461626 |
| Acute kidney injury | disease | 21719790 |
| Acute kidney injury | disease | 30268831 |
| Acute kidney injury | disease | 31034781 |
| Acute kidney injury | disease | 21975863 |
| Acute Lung Injury | disease | 25512625 |
| Adenocarcinoma | group | 21550230 |
| Adenocarcinoma | group | 25499851 |
| Adenoma | group | 26223300 |
| Adenomatous Polyposis Coli | disease | 20971552 |
