1. 靶点主信息
| NCBI Gene id: | 2729 |
| Gene_name: | GCLC |
| Gene alias: | GCL; GCS; GLCL; GLCLC |
| Map location: | 6p12.1 |
| Type of gene: | protein-coding |
| Description: | glutamate-cysteine ligase catalytic subunit |
| OMIM_id: | 606857 |
| HGNC_id: | 4311 |
| Ensembl_id: | ENSG00000001084 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 菝葜 | Smilax Chi | - |
| 白蒺藜 | Tribulus fruit | Fructus Tribuli |
| 白屈菜 | Chelidonii Herba | - |
| 白药子 | Radix Stephaniae Cepharanthae. | - |
| 萆薢 | Hypoglaucous Collett Yam Equivalent plant: Dioscor | Dioscorea hypoglauca [Syn. Dioscorea collettii var |
| 柴胡 | root of Chinese Thorowax | Radix Bupleuri |
| 车前子 | seed of Asiatic pantain | Semen Plantaginis |
| 穿龙薯蓣 | Nippon Yam Equivalent plant: Dioscorea nipponica s | Dioscorea nipponica |
| 穿山龙 | Ningpo Yam Rhizome | Rhizoma Dioscoreae Nipponicae |
| 刺果松 | Bristlecone Pine | Pinus aristata |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 487-52-5 | 紫铆因 | Butein | 5281222 |
| 480-40-0 | 白杨素 | Chrysin | 5281607 |
| 19057-60-4 | 薯蓣皂苷 | Dioscin | 119245 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 26348276 |
| Autoimmune Diseases | group | 26996065 |
| Bone neoplasms | group | 29497056 |
| Cardiotoxicity | disease | 29524841 |
| Colorectal Neoplasms | group | 26515162 |
| Fatty Liver, Alcoholic | disease | 24146112 |
| Infarction, Middle Cerebral Artery | disease | 25772012 |
| Inflammation | phenotype | 30738841 |
| Insulin Resistance | phenotype | 30158592 |
| Ischemic stroke | disease | 25772012 |
