1. 靶点主信息
| NCBI Gene id: | 2081 |
| Gene_name: | ERN1 |
| Gene alias: | IRE1; IRE1P; IRE1a; hIRE1p |
| Map location: | 17q23.3 |
| Type of gene: | protein-coding |
| Description: | endoplasmic reticulum to nucleus signaling 1 |
| OMIM_id: | 604033 |
| HGNC_id: | 3449 |
| Ensembl_id: | ENSG00000178607 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 白鲳 | Drug Sweetflag | Acorus calamus |
| 草果 | Tsaoko | Fructus tsaoko |
| 粗毛甘草 | Hirsute Licorice | Glycyrrhiza aspera |
| 粗叶悬钩子 | Roughleaf Raspberry | Rubus alceaefolius |
| 大花哥纳香 | Bigflower Goniothalamus | Goniothalamus griffithii |
| 大花紫薇 | Queen Crapemyrtle | Lagerstroemia speciosa |
| 大枣 | Jujube Chinese date | Fructus Zizyphi Jujubae |
| 当归 | root of Chinese Angelica | Radix Angelicae sinensis |
| 地骨皮 | root - bark of Chinese Wolfberry | Cortex Lycii Radicis |
| 冬瓜皮 | Chinese Waxgourd Peel | Exocarpium Benincasae |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 471-53-4 | - | beta-Glycyrrhetic acid | 18526330 |
| 13956-29-1 | - | Cannabidiol | 644019 |
| 4547-24-4 | 科罗索酸 | Corosolic acid | 6918774 |
| 458-37-7 | 姜黄素 | Curcumin | 969516 |
| 480-39-7 | 乔松素 | Pinocembrin | 68071 |
| 14605-22-2 | 牛磺熊去氧胆酸 | Tauroursodeoxycholic acid | 9848818 |
| 62949-76-2 | xanthoangelol | Xanthoangelol | 643007 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 31034781 |
| Adenocarcinoma | group | 25499851 |
| Adenomatous Polyposis Coli | disease | 20971552 |
| Alzheimer's Disease | disease | 30951849 |
| Alzheimer's Disease | disease | 30610916 |
| Angelman Syndrome | disease | 31503547 |
| Anxiety | disease | 30542090 |
| Anxiety | disease | 31109198 |
| Anxiety | disease | 30538288 |
| Anxiety | disease | 30157131 |
