1. 药材主信息
| 中文名称: | 地骨皮 |
| 英文名称: | root - bark of Chinese Wolfberry |
| 拉丁名称: | Cortex Lycii Radicis |
| 使用部位: | - |
| 功用: | To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung. |
| 适用症: | 1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 21637-25-2 | - | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | 51402807 |
| 1078-61-1 | 3-(3,4-二羟基苯基)丙酸 | 3-(3,4-Dihydroxyphenyl)propionic acid | 348154 |
| 53170-93-7 | 3-羟基-1-(4-羟基苯基)丙烷-1-酮 | 3-Hydroxy-1-(4-hydroxyphenyl)propan-1-one | 638759 |
| 2237-36-7 | 4-甲氧基水杨酸 | 4-Methoxysalicylic acid | 75231 |
| 89886-42-0 | 9S-羟基-10E,12Z,15Z-十八碳三烯酸 | 9-Hydroxy-10,12,15-octadecatrienoic acid | 6439873 |
| 10075-11-3 | 9(R)-hydroxy-10(E),12(Z)-octadecadienoic acid | 9R-hydroxy-10E,12Z-octadecadienoic acid | 16061059 |
| 480-44-4 | 金合欢素;刺槐素 | Acacetin | 5280442 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 480-10-4 | 紫云英苷 | Astragalin | 5282102 |
| 51-55-8 | 阿托品 | Atropine | 174174 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 21445586 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Atrial Fibrillation | disease | 21906601 |
| Birth Weight | phenotype | 27655442 |
| Blood Pressure | phenotype | 28143892 |
| Body mass index | phenotype | 27655442 |
| Carcinogenesis | phenotype | 24169354 |
| Carcinoma | group | 24169354 |
| Choline Deficiency | disease | 31120771 |
| Colitis | disease | 25281414 |
| Colorectal Neoplasms | group | 24827130 |
