1. 药材主信息
| 中文名称: | 粗叶悬钩子 |
| 英文名称: | Roughleaf Raspberry |
| 拉丁名称: | Rubus alceaefolius |
| 使用部位: | root and leaf |
| 功用: | To clear heat and disinhibit damp, stanch bleeding, dispel stasis. |
| 适用症: | Hepatitis, dysentery, enteritis, mastitis, stomatitis, march hematoglobinuria, bleeding due to external injury, liver spleen enlargement, knocks and falls, wind-damp bone pain. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 82464-35-5 | 3-氧代甘遂-7,24-二烯-21-酸 | 3-Oxotirucalla-7,24-dien-21-oic acid | 158100 |
| 124151-38-8 | 粗叶悬钩子甙 | Alcesefoliside | 11828754 |
| 481-72-1 | 芦荟大黄素 | Aloe emodin | 10207 |
| 2074-53-5 | 维生素 E | Alpha-Tocopherol | 14985 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 472-15-1 | 白桦脂酸 | Betulinic Acid | 64971 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 4547-24-4 | 科罗索酸 | Corosolic acid | 6918774 |
| 133352-34-8 | - | Corossoline | 11071966 |
| 6624-79-9 | 正三十二醇 | Dotriacontanol | 96117 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30897821 |
| CCL27 | ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27 | 9p13.3 | 25832436 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cardiovascular Diseases | group | 26869350 |
| Diabetes | disease | 28707095 |
| Head and Neck Neoplasms | group | 24157255 |
| Hyperglycemia | disease | 28707095 |
| leukemia | disease | 27270429 |
| Liver neoplasms | group | 23848338 |
| Myocardial Infarction | disease | 23291593 |
| Myocardial Reperfusion Injury | phenotype | 23291593 |
| Nasopharyngeal carcinoma | disease | 31731581 |
| Osteoporosis | disease | 25832436 |
