1. 成分信息
| 英文名: | Berberine |
| 中文名: | 小檗碱 |
| CAS编号: | 2086-83-1 |
| 分子式: | C20H18NO4+ |
| 分子量: | 336.4 |
| SMILES: | COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 白蔹 | root of Japanese Ampelopsis | Radix Ampelopsis |
| 白茅根 | Golden-seal | Hydrastis canadensis |
| 白屈菜 | Chelidonii Herba | - |
| 白屈菜根 | Radix Chelidonii maji | - |
| 白药子 | Radix Stephaniae Cepharanthae. | - |
| 瓣蕊唐松草 | Petalformed Meadowrue | Thalictrum petaloideum |
| 长距延胡索 | Longspur Corydalis | Corydalis longicalcarata |
| 齿瓣延胡索 | Toothedpetal Corydalis | Corydalis remota [Syn. Corydalis bulbosa var. typi |
| 川黄连 | rhizome of Chinese Goldthread | Rhizoma Coptidis |
| 川楝子 | Szechwan Chiberry Fruit | Fructus Meliae Toosendan |
3. 相关靶点
| 基因靶点 | 靶点位置 | 参考文献 |
| ANXA5 | 4q27 | 25682924 |
| BAX | 19q13.33 | 25682924 |
| CASP3 | 4q35.1 | 21496227 |
| CASP3 | 4q35.1 | 28990249 |
| CCNA1 | 13q13.3 | 25682924 |
| CCNB1 | 5q13.2 | 25682924 |
| CDK1 | 10q21.2 | 25682924 |
| CDK4 | 12q14.1 | 25682924 |
| CDKN1A | 6p21.2 | 25682924 |
| DNM1L | 12p11.21 | 31037132 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Diabetes Mellitus, Experimental | disease | 27067643 |
| Diabetes Mellitus, Experimental | disease | 20304443 |
| Glucose tolerance test | phenotype | 20304443 |
| Hyperglycemia | disease | 27067643 |
| Insulin Resistance | phenotype | 22019891 |
| Insulin Resistance | phenotype | 20304443 |
| Left Ventricular Hypertrophy | disease | 31371114 |
| Neoplasms, Glandular and Epithelial | group | 28990249 |
| ovarian neoplasm | disease | 28990249 |
