科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 制首乌
英文名称: Prepared FLeeceflower Root
拉丁名称: Radix Polygoni Multiflori Preparata
使用部位: Radix Polygoni Multiflori
功用: Treatment of anemia, dizziness and tinnitus, premature greying of the hair and beard, soreness and weakness of the loins and the knees, abnormal uterine bleeding and excessive leukorrhea, general debility in chronic malaria, hyperlipemia.
适用症: Treatment of anemia, dizziness and tinnitus, premature greying of the hair and beard, soreness and weakness of the loins and the knees, abnormal uterine bleeding and excessive leukorrhea, general debility in chronic malaria, hyperlipemia.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
83-46-5 β-谷甾醇 Beta-Sitosterol 222284
518-82-1 大黄素 Emodin 3220
118525-40-9 淫羊藿素 Icaritin 5318980
521-61-9 大黄素甲醚 Physcione 10639
478-43-3 大黄酸 Rhein 10168

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 24157255
ALPL AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP 1p36.12 25832436
ALPP ALP; ALPI; IAP; PALP; PLAP; PLAP-1 2q37.1 25832436
ASRGL1 ALP; ALP1; CRASH 11q12.3 25832436
ATHS ALP 19p13.3-p13.2 25832436
ATRNL1 ALP; bA338L11.1; bA454H24.1 10q25.3 25832436
BAX BCL2L4 19q13.33 30674340
BCL2 Bcl-2; PPP1R50 18q21.33 30674340
BGLAP BGP; OC; OCN 1q22 25832436
CASP1 ICE; IL1BC; P45 11q22.3 24721152

4. 相关疾病