1. 药材主信息
| 中文名称: | 南丹参 |
| 英文名称: | Bowley Sage |
| 拉丁名称: | Salvia bowleyana |
| 使用部位: | root |
| 功用: | To quicken blood and transform stasis, regulate menstruation and relieve pain. |
| 适用症: | Chest impediment and angina, vexation, heart palpitation, pain in stomach duct and abdomen, menstrual disorder [=menoxenia], menstrual pain, menstrual block, postpartum stasis stagnation abdominal pain, flooding and spotting, liver spleen enlargement, arthralgia, mounting qi (hernia), swelling of sores. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 99-50-3 | 原儿茶酸 | 3,4-Dihydroxybenzoic acid | 72 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 35825-57-1 | 隐丹参酮 | Cryptotanshinone | 160254 |
| 87205-99-0 | 二氢丹参酮I | Dihydrotanshinone I | 11425923 |
| 18887-19-9 | 丹参酮甲酯 | Methyl tanshinonate | 14610613 |
| 67656-29-5 | - | Methylenetanshinquinone | 105118 |
| 139-85-5 | 原儿茶醛 | Protocatechualdehyde | 8768 |
| 115841-09-3 | 丹酚酸C | Salvianolic acid C | 13991590 |
| 112-92-5 | 十八醇 | Stearyl Alcohol | 8221 |
| 105351-70-0 | Tanshinlactone | Tanshinlactone | 5321617 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ACTA2 | ACTSA | 10q23.31 | 28257144 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 22154085 |
| AKT2 | HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA | 19q13.2 | 24973798 |
| BAX | BCL2L4 | 19q13.33 | 30691497 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 28257144 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26564229 |
| CASP7 | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 | 10q25.3 | 26564229 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 26564229 |
| CCN2 | CTGF; HCS24; IGFBP8; NOV2 | 6q23.2 | 28257144 |
| COL1A1 | CAFYD; EDSARTH1; EDSC; OI1; OI2; OI3; OI4 | 17q21.33 | 28257144 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 29158049 |
| Atherosclerosis | disease | 25572313 |
| Bone neoplasms | group | 30691497 |
| Glioma | disease | 28492557 |
| Glucose Metabolism Disorders | group | 24973798 |
| Insulin Resistance | phenotype | 24973798 |
| leukemia | disease | 26564229 |
| Liver Cirrhosis | disease | 28257144 |
| Osteosarcoma | disease | 30691497 |
| Polycystic Ovary Syndrome | disease | 24973798 |
