科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 黑大豆
英文名称: Black Soyabean
拉丁名称: Glycine max
使用部位: black seed
功用: To quicken blood and disinhibit water, dispel wind and resolve toxin, fortify spleen and boost kidney.
适用症: Edema distention fullness, wind toxin and beriberi, jaundice edema, kidney vacuity lumbago, enuresis, wind impediment and hypertonicity of sinews, postpartum wind tetany, clenched jaw, swelling toxin of welling abscess and sore, drug poisoning, food poisoning.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
6000-40-4 - (2R)-2,3-Dihydroxypropanoic acid 439194
83-46-5 β-谷甾醇 Beta-Sitosterol 222284
462-94-2 - Cadaverine 273
20972-07-0 - Campesteryl Ferulate 15056832
585-84-2 顺乌头酸 cis-Aconitic acid 643757
469-38-5 环阿屯醇 Cycloartenol 92110
486-66-8 大豆苷元(黄豆苷元) Daidzein 5281708
83-46-5 - gamma-Sitosterol 457801
446-72-0 染料木素 Genistein 5280961
66026-80-0 染料木素8-C-葡萄糖苷 Genistein 8-C-glucoside 5281757

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCA1 ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD 9q31.1 26558782
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG1 ABC8; WHITE1 21q22.3 26558782
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
APOE AD2; APO-E; ApoE4; LDLCQ5; LPG 19q13.32 26558782
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941
BACE1 ASP2; BACE; HSPC104 11q23.3 24107941
MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK 22q11.22 22931352

4. 相关疾病