1. 靶点主信息
NCBI Gene id: | 5599 |
Gene_name: | MAPK8 |
Gene alias: | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c |
Map location: | 10q11.22 |
Type of gene: | protein-coding |
Description: | mitogen-activated protein kinase 8 |
OMIM_id: | 601158 |
HGNC_id: | 6881 |
Ensembl_id: | ENSG00000107643 |
2. 相关药材
中文名称 | 英文名称 | 拉丁文名称 |
矮地茶 | Japanese Ardisia Herb | Ardisiae japonicae |
艾叶 | leaf of Argy Wormwood | Folium Artemisiae Argyi |
安息香 | Benzoin | Benzoinum |
凹叶厚朴 | Twolobed Officinal Mangolia | Magnolia biloba |
凹叶瑞香 | Retuseleaf Daphne | Daphne retusa |
八角茴香 | Chinese Star Anise | Fructus Anisi Stellati |
菝葜 | Smilax Chi | - |
白鲳 | Drug Sweetflag | Acorus calamus |
白附子 | rhizome of Giant Typhonium | Rhizoma Typhonii |
白果紫草 | Common Gromwell | Lithospermum officinale |
3. 相关成分
CAS号 | 中文名称 | 英文名称 | 参考文献 |
471-53-4 | - | beta-Glycyrrhetic acid | 18526330 |
33570-04-6 | 白果内酯 | Bilobalide | 73581 |
487-52-5 | 紫铆因 | Butein | 5281222 |
13956-29-1 | - | Cannabidiol | 644019 |
56-25-7 | 斑蝥素 | Cantharidin | 5944 |
34157-83-0 | 雷公藤红素 | Celastrol | 122724 |
104-55-2 | 桂皮醛(反式肉桂醛) | Cinnamaldehyde | 637511 |
73-03-0 | 虫草素 | Cordycepin | 6303 |
4547-24-4 | 科罗索酸 | Corosolic acid | 6918774 |
2222-07-3 | 葫芦素 I | Cucurbitacin I | 5281321 |
4. 相关疾病
疾病名称 | 疾病类型 | 参考文献 |
Acne Vulgaris | disease | 22763784 |
Acute kidney injury | disease | 30268831 |
Acute kidney injury | disease | 26348276 |
Acute kidney injury | disease | 31034781 |
Acute kidney injury | disease | 21975863 |
Acute Lung Injury | disease | 25512625 |
Acute Lung Injury | disease | 29243243 |
Acute Lung Injury | disease | 21279327 |
Adenocarcinoma | group | 25499851 |
Adenoma | group | 26223300 |