1. 靶点主信息
| NCBI Gene id: | 3845 |
| Gene_name: | KRAS |
| Gene alias: | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 |
| Map location: | 12p12.1 |
| Type of gene: | protein-coding |
| Description: | KRAS proto-oncogene, GTPase |
| OMIM_id: | 190070 |
| HGNC_id: | 6407 |
| Ensembl_id: | ENSG00000133703 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 艾叶 | leaf of Argy Wormwood | Folium Artemisiae Argyi |
| 凹叶厚朴 | Twolobed Officinal Mangolia | Magnolia biloba |
| 八角茴香 | Chinese Star Anise | Fructus Anisi Stellati |
| 菝葜 | Smilax Chi | - |
| 白扁豆 | White Hyacinth Bean | Semen Lablab Album |
| 白附子 | rhizome of Giant Typhonium | Rhizoma Typhonii |
| 白果叶 | Ginkgo Leaf | Ginkgo biloba |
| 白花前胡 | Whiteflower Hogfennel | Peucedanum praeruptorum |
| 白花蛇舌草 | all - grass of Spreading Hedyotis | Herba Hedyotis Diffusae |
| 败酱草 | All - grass of Dahurian Patrinia | Herba Patriniae |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 303156-68-5 | - | (-)-Rasfonin | 11259090 |
| 577-85-5 | 3-羟基黄酮 | 3-Hydroxyflavone | 11349 |
| 471-53-4 | - | beta-Glycyrrhetic acid | 18526330 |
| 305-84-0 | L-肌肽 | Carnosine | 439224 |
| 91-64-5 | 香豆素 | Coumarin | 323 |
| 35354-74-6 | 和厚朴酚 | Honokiol | 72303 |
| 7512-17-6 | - | N-Acetyl-D-Glucosamine | 439174 |
| 84573-16-0 | Rocaglamide | Rocaglamide | 331783 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 21279327 |
| Adenocarcinoma | group | 24267912 |
| adiposity | phenotype | 28100511 |
| Arthritis, Experimental | disease | 24838404 |
| Atherosclerosis | disease | 23559625 |
| Brain Ischemia | disease | 24938837 |
| Brain Neoplasms | group | 22259050 |
| Carcinoma, Ovarian Epithelial | disease | 25332332 |
| Carcinoma, Pancreatic Ductal | disease | 24568222 |
| Cardiomegaly | phenotype | 25871545 |
