1. 靶点主信息
NCBI Gene id: | 3791 |
Gene_name: | KDR |
Gene alias: | CD309; FLK1; VEGFR; VEGFR2 |
Map location: | 4q12 |
Type of gene: | protein-coding |
Description: | kinase insert domain receptor |
OMIM_id: | 191306 |
HGNC_id: | 6307 |
Ensembl_id: | ENSG00000128052 |
2. 相关药材
中文名称 | 英文名称 | 拉丁文名称 |
波叶大黄 | Rheum undulatum Linn | - |
茶叶 | Common Tea | Camellia sinensis [Syn. Thea sinensis] |
茺蔚子 | Motherwort Fruit | Fructus Leonuri |
刺马前子 | Aculeate Poisonnut | Strychnos aculeata |
大黄 | root and rhziome of Sorrel Rhubarb | Radix et Rhizoma Rhei |
大黄茎 | Rhizoma seu Plantula Rhei palmati | - |
大叶香茶菜 | Largeleaf Rabdosia | Rabdosia macrophylla |
倒扣草 | Achyranthis Asperae Herba | - |
地瓜子 | Wayaka Yambean Seed | Pachyrhizus erosus |
冬淩草 | Blushred Rabdosia | Rabdosia rubescens |
3. 相关成分
CAS号 | 中文名称 | 英文名称 | 参考文献 |
130-15-4 | - | 1,4-Naphthoquinone | 8530 |
63428-84-2 | 马钱子碱 | Brucine | 442021 |
989-51-5 | 表没食子儿茶素没食子酸酯 | Epigallocatechin Gallate | 65064 |
60-82-2 | 根皮素 | Phloretin | 4788 |
82-08-6 | Rottlerin | Rottlerin | 5281847 |
35287-69-5 | - | Secalonic acid D | 73431 |
14605-22-2 | 牛磺熊去氧胆酸 | Tauroursodeoxycholic acid | 9848818 |
38748-32-2 | 雷公藤甲素 | Triptolide | 107985 |
111408-21-0 | - | Tylophorine, (-)- | 10883727 |
4. 相关疾病
疾病名称 | 疾病类型 | 参考文献 |
Acne Vulgaris | disease | 22763784 |
Acute Lung Injury | disease | 31186013 |
Adenocarcinoma | group | 25661734 |
Alzheimer's Disease | disease | 22300765 |
Anti-Glomerular Basement Membrane Disease | disease | 21544063 |
Aortic Diseases | group | 24379182 |
Aortic Valve Stenosis | disease | 23928865 |
Arthritis, Experimental | disease | 26473505 |
Arthritis, Gouty | disease | 29959312 |
Ascites | phenotype | 20872277 |