1. 靶点主信息
| NCBI Gene id: | 1786 |
| Gene_name: | DNMT1 |
| Gene alias: | ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI |
| Map location: | 19p13.2 |
| Type of gene: | protein-coding |
| Description: | DNA methyltransferase 1 |
| OMIM_id: | 126375 |
| HGNC_id: | 2976 |
| Ensembl_id: | ENSG00000130816 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 白附子 | rhizome of Giant Typhonium | Rhizoma Typhonii |
| 白花蛇舌草 | all - grass of Spreading Hedyotis | Herba Hedyotis Diffusae |
| 败酱草 | All - grass of Dahurian Patrinia | Herba Patriniae |
| 白木香 | Chinese Eaglewood | Aquilaria sinensis |
| 白头翁 | Root of Chinese Pulsatilla | Radix Pulsatillae |
| 半枝莲 | all - grass of Barbed Skullcap | Herba Scutellariae barbatae |
| 秘鲁钩藤 | Una de Gato (Cat’s Claw) | Uncaria tomentosa |
| 薄荷 | Mentha, Peppermint | herba Menthae |
| 草豆蔻 | Katsumada Galangal | Alpinia katsumadai |
| 茶叶 | Common Tea | Camellia sinensis [Syn. Thea sinensis] |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 4368-28-9 | - | (1R,5R,6R,7R,9S,11S,13S,14R)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-ene-5,9,12,13,14-pentol | 139251219 |
| 1090-65-9 | 山姜素 | 7-Hydroxy-5-methoxy-2-phenylchroman-4-one | 4053302 |
| 25654-31-3 | 大麻萜酚 | Cannabigerol | 5315659 |
| 989-51-5 | 表没食子儿茶素没食子酸酯 | Epigallocatechin Gallate | 65064 |
| 478-43-3 | 大黄酸 | Rhein | 10168 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acne Vulgaris | disease | 22763784 |
| Alzheimer's Disease | disease | 22300765 |
| Anti-Glomerular Basement Membrane Disease | disease | 21544063 |
| Arthritis, Experimental | disease | 26473505 |
| Bladder pain syndrome | disease | 30157135 |
| Blood Pressure | phenotype | 23103594 |
| Blood Pressure | phenotype | 23570977 |
| Brain Edema | phenotype | 25582287 |
| Brain Neoplasms | group | 21257259 |
| Brain Waves | phenotype | 30228120 |
