1. 药材主信息
| 中文名称: | 白毛夏枯草 |
| 英文名称: | all - grass of Decumbent Bugle |
| 拉丁名称: | Herha Ajugae Ciliatae |
| 使用部位: | whole herb |
| 功用: | 1. To clear lung-heat, eliminate phlegm and relieve cough. 2. to clear away heat and toxic material, and relieve carbuncle. 3. Clear away heat to cool the blood. 4. Lower blood pressure. |
| 适用症: | Swelling pain in throat, lung heat cough, pulmonary welling abscess, red eyes with gall, dysentery, swollen welling abscess and clove sores, poisonous snake bite, knocks and falls. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 465-18-9 | 猪苓酸C | (2R)-2-[(5R,10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid | 9805290 |
| 18069-14-2 | (20R,22R)-2Β,3Β,5Α,14Α,20,22,25-七羟基胆甾-7-烯-6-酮 | 2beta,3beta,5beta,14,20,22R,25-Heptahydroxycholest-7-en-6-one | 441833 |
| 6926-14-3 | 乙酰哈巴苷 | 8-O-Acetylharpagide | 9978650 |
| 132922-44-2 | - | Ajugacumbin F | 6442776 |
| 42975-12-2 | - | Ajugalactone | 181744 |
| 122587-82-0 | - | Ajugamarin A2 | 14356994 |
| 122616-88-0 | - | Ajugamarin H1 | 21629954 |
| 124961-67-7 | 筋骨草素L2 | Ajugamarin L2 | 6442458 |
| 23044-80-6 | 筋骨草甾酮C | Ajugasterone C | 441826 |
| 73030-71-4 | 白术内酯III | Atractylenolide III | 155948 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26931119 |
| ATF4 | CREB-2; CREB2; TAXREB67; TXREB | 22q13.1 | 26661339 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21122982 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21122982 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 26661339 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21122982 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 27756327 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 21122982 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 27756327 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 21122982 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Lung Neoplasms | group | 26661339 |
| Multiple Myeloma | disease | 21122982 |
| Pancreatic Neoplasm | disease | 27756327 |
| Parkinson Disease | disease | 28780078 |
