1. 药材主信息
| 中文名称: | 皂角刺 |
| 英文名称: | spine of Chinese Honeylocust |
| 拉丁名称: | Spi gleditsiae |
| 使用部位: | - |
| 功用: | To cause subsidence of swelling, to draw out of pus, and to kill parasites. |
| 适用症: | 1. To relieve carbuncle and drain pus. For the early stage of carbuncle or carbuncle with unruptured abscess. 2. To expel wind and kill parasites. For tinea infection and leprosy. |
| 毒副作用: | Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 35323-91-2 | - | (+)-Epicatechin | 182232 |
| 111003-33-9 | - | (-)-Taxifolin | 712316 |
| 7720-39-0 | - | 1H-Imidazol-2-amine | 82140 |
| 4339-72-4 | 齐敦果酸乙酸酯 | 3-O-Acetyloleanolic acid | 151202 |
| 19072-58-3 | - | 4-Hydroxy-3-methoxybenzamide | 354088 |
| 31721-94-5 | 5,7-二羟基色原酮 | 5,7-Dihydroxychromone | 5281343 |
| 73-24-5 | 腺嘌呤 | Adenine | 190 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| ADAM9 | CORD9; MCMP; MDC9; Mltng | 8p11.22 | 31438640 |
| AHSA1 | AHA1; C14orf3; hAha1; p38 | 14q24.3 | 31540162 |
| AIMP2 | HLD17; JTV-1; JTV1; P38 | 7p22.1 | 31540162 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31540162 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Bone neoplasms | group | 29270805 |
| Esophageal Neoplasms | group | 26603620 |
| Inflammation | phenotype | 31540162 |
| Kidney Neoplasm | disease | 31438640 |
| Liver diseases | group | 24107776 |
| Longevity | phenotype | 30279143 |
| Lung Neoplasms | group | 29247826 |
| Melanoma, Experimental | disease | 20840540 |
| Neoplasm Metastasis | phenotype | 31438640 |
| Neoplasm Metastasis | phenotype | 20840540 |
