1. 药材主信息
| 中文名称: | 藏边打黄 |
| 英文名称: | Austral Rhubarb |
| 拉丁名称: | Rheum emodi [Syn. Rheum australe] |
| 使用部位: | root and rhizome |
| 功用: | To clear heat and resolve toxin, stanch bleeding and engender flesh. |
| 适用症: | Lung heat cough, swelling pain in throat, swelling toxin of welling abscess and sore, bleeding due to external injury, hematochezia. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 481-72-1 | 芦荟大黄素 | Aloe emodin | 10207 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 53823-09-9 | - | Cascaroside C | 46173832 |
| 53861-35-1 | - | Cascaroside D | 46173831 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 154-23-4 | (+)-儿茶素 | Cianidanol | 9064 |
| 154-23-4 | (+)-儿茶素 | Cianidanol | 9064 |
| 132-60-5 | 2-苯基喹啉-4-羧酸 | Cinchophen | 8593 |
| 490-46-0 | 表儿茶素 | EC;Epicatechin | 72276 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BAX | BCL2L4 | 19q13.33 | 30674340 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30674340 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
| CASP1 | ICE; IL1BC; P45 | 11q22.3 | 24721152 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30447302 |
| Diabetic Nephropathy | disease | 21195168 |
| Head and Neck Neoplasms | group | 24157255 |
| Inflammation | phenotype | 24721152 |
| leukemia | disease | 27270429 |
| Liver neoplasms | group | 23848338 |
| Nasopharyngeal carcinoma | disease | 31731581 |
| Osteoporosis | disease | 25832436 |
| Osteoporosis | disease | 27692562 |
| Pancreatic Neoplasm | disease | 30674340 |
