1. 药材主信息
| 中文名称: | 延胡索 |
| 英文名称: | Corydalis tuber |
| 拉丁名称: | Rhizoma Corydalis |
| 使用部位: | rhizome |
| 功用: | 1. To invigorate blood and promote qi circulation; 2. To stop pain |
| 适用症: | Chest and rib-side pain, pain in stomach duct and abdomen, neuralgia, gastrointestinal spasm, amenorrhea and dysmenorrhea, postpartum stasis stagnation abdominal pain, painful swelling from knocks and falls. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 13063-54-2 | D-四氢药根碱 | (+)-Corypalmine | 12304090 |
| 5083-88-5 | - | (+)-Thaliporphine | 6992288 |
| 2086-96-6 | - | (R)-Canadine | 443422 |
| 261613-72-3 | - | (R)-nonacosan-10-ol | 342803 |
| 6451-73-6 | 金黄紫堇碱 | (S)-Scoulerine | 439654 |
| 483-34-1 | 四氢非洲防己碱 | (S)-Tetrahydrocolumbamine | 440229 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
| 41917-45-7 | - | 5-(3,4-Methylenedioxyphenyl)pentanoic acid | 5321853 |
| 24240-04-8 | 别隐品碱 | Allocryptopine | 98570 |
| 24240-04-8 | 别隐品碱 | Allocryptopine | 98570 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27154977 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31819036 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ANXA5 | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 | 4q27 | 25682924 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Bone Resorption | phenotype | 31145860 |
| Brain Neoplasms | group | 26472194 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Diabetes Mellitus, Experimental | disease | 27067643 |
| Diabetes Mellitus, Experimental | disease | 20304443 |
| Glioma | disease | 26472194 |
| Glucose tolerance test | phenotype | 20304443 |
| Head and Neck Neoplasms | group | 24157255 |
| Hyperglycemia | disease | 27067643 |
| Inflammation | phenotype | 24388848 |
