1. 药材主信息
| 中文名称: | 小叶贯众 |
| 英文名称: | Matteuccia Frond |
| 拉丁名称: | Matteuccia struthiopteris |
| 使用部位: | rhizome |
| 功用: | To clear heat and resolve toxin, kill worms, stanch bleeding. |
| 适用症: | Febrile diseases macular eruption, parotitis, damp-heat sore toxin, abdominal pain due to ascariasis, oxyuria disease, red dysentery and bloody stool, hematuria, blood ejection, spontaneous external bleeding, flooding and spotting [=metrorrhagia and metrostaxis]. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-32-1 | 花生四烯酸 | Arachidonic Acid | 444899 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 3604-87-3 | - | Ecdysone | 19212 |
| 83-46-5 | - | gamma-Sitosterol | 457801 |
| 13408-56-5 | Ponasterone A | Ponasterone A | 115127 |
| 20117-33-3 | - | Ponasteroside A | 12314455 |
| 18089-44-6 | - | Pterosterone | 441836 |
| 537-42-8 | 紫檀芪 | Pterostilbene | 5281727 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28327179 |
| ATF4 | CREB-2; CREB2; TAXREB67; TXREB | 22q13.1 | 31138785 |
| BAX | BCL2L4 | 19q13.33 | 24417315 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 24417315 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 24417315 |
| CAT | - | 11p13 | 24417315 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 21291235 |
| EIF2S1 | EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A | 14q23.3 | 31138785 |
| FOXO1 | FKH1; FKHR; FOXO1A | 13q14.11 | 31063760 |
| FOXO3 | AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A | 6q21 | 31063760 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 27364556 |
| Carcinogenesis | phenotype | 30120247 |
| Carcinoma, Lewis Lung | disease | 28327179 |
| Colonic Neoplasms | group | 21291235 |
| Diabetes | disease | 24417315 |
| Inflammation | phenotype | 27364556 |
| Inflammation | phenotype | 25746774 |
| Liver neoplasms | group | 31138785 |
| Lung Neoplasms | group | 28796247 |
| Lung Neoplasms | group | 28327179 |
