1. 药材主信息
| 中文名称: | 橘核 |
| 英文名称: | Tangerine Seed |
| 拉丁名称: | Semen Citri Reticulatae |
| 使用部位: | seed |
| 功用: | To regulate the flow of qi, cause subsidence of modulation, and relieve pain. |
| 适用症: | Mounting qi, painful swollen testes, mammary welling abscess, lumbago, bladder qi pain. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 751-29-1 | - | (2E)-3-[(3aS,5aR,6R,7R,9aR,9bR,10aS)-3-(Furan-3-yl)-7-(2-hydroxypropan-2-yl)-3a,6,9a-trimethyl-1,9-dioxododecahydronaphtho[2,1-c]oxireno[d]pyran-6-yl]prop-2-enoic acid | 54611038 |
| 5655-61-8 | - | (2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl acetate | 44630108 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
| 66851-47-6 | - | 1,2-Benzenedi(carboxylic-14C)acid, dibutyl ester | 171810 |
| 3777-69-3 | 2-戊基呋喃 | 2-Pentylfuran | 19602 |
| 7541-49-3 | 叶绿醇 | 3,7,11,15-Tetramethyl-2-hexadecen-1-OL | 5366244 |
| 562-74-3 | 4-松油醇 | 4-Terpineol, (+/-)- | 11230 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| DGKD | DGK-delta; DGKdelta; dgkd-2 | 2q37.1 | 28707095 |
| GCG | GLP-1; GLP1; GLP2; GRPP | 2q24.2 | 23471488 |
| HSPA4 | APG-2; HEL-S-5a; HS24/P52; HSPH2; RY; hsp70; hsp70RY | 5q31.1 | 29017971 |
| ICAM1 | BB2; CD54; P3.58 | 19p13.2 | 21542832 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 30975172 |
| MAP3K5 | ASK1; MAPKKK5; MEKK5 | 6q23.3 | 30975172 |
| MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | 6p21.31 | 30975172 |
| MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | 10q11.22 | 30975172 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 21542832 |
| PRKAA1 | AMPK; AMPKa1 | 5p13.1 | 31181335 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus | group | 25411288 |
| Encephalitis | disease | 30975172 |
| Glucose tolerance test | phenotype | 25411288 |
| Hyperalgesia | phenotype | 30975172 |
| Hyperalgesia | phenotype | 29017971 |
| Hyperglycemia | disease | 23471488 |
| Hyperglycemia | disease | 28707095 |
| Inflammation | phenotype | 29017971 |
| Insulin Resistance | phenotype | 25411288 |
