1. 药材主信息
| 中文名称: | 鹅绒藤 |
| 英文名称: | Chinese Swallowwort |
| 拉丁名称: | Cynanchum chinense |
| 使用部位: | white juice in stem |
| 功用: | To clear heat and resolve toxin, disperse accumulation and fortify stomach, disinhibit water and disperse edema. |
| 适用症: | Child food accumulation, child gan accumulation, gastritis, gastritis with edema, duodenal ulcer, wart. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 645-08-9 | 异香草酸 | 3-Hydroxy-4-methoxybenzoic acid | 12575 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 154-23-4 | (+)-儿茶素 | Cianidanol | 9064 |
| 143502-52-7 | - | Cynanester A | 132563 |
| 490-46-0 | 表儿茶素 | EC;Epicatechin | 72276 |
| 970-74-1 | 表没食子儿茶素 | Epigallocatechin | 72277 |
| 40957-99-1 | 5'-甲氧基松脂素 | Medioresinol | 181681 |
| 474-58-8 | 刺五加苷A(胡萝卜苷) | Sitogluside | 5742590 |
| 520-32-1 | 苜蓿素 | Tricin | 5281702 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| CAT | - | 11p13 | 29179721 |
| CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | 9p24.1 | 27378243 |
| CDC37 | P50CDC37 | 19p13.2 | 21871133 |
| CDK4 | CMM3; PSK-J3 | 12q14.1 | 21871133 |
| COLQ | CMS5; EAD | 3p25.1 | 28056971 |
| CSNK2A2 | CK2A2; CK2alpha'; CSNK2A1 | 16q21 | 21871133 |
| CXCL10 | C7; IFI10; INP10; IP-10; SCYB10; crg-2; gIP-10; mob-1 | 4q21.1 | 28378188 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Blood Pressure | phenotype | 28143892 |
| Cardiomyopathies | group | 31064352 |
| Diabetic Nephropathy | disease | 21195168 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Fibrosis | phenotype | 28143892 |
| Inflammation | phenotype | 27374313 |
| Lung Neoplasms | group | 21550230 |
| Multiple Myeloma | disease | 21871133 |
| Neoplasm Metastasis | phenotype | 31182131 |