1. 药材主信息
| 中文名称: | 大叶菜 |
| 英文名称: | Doederlein’s Spikemoss |
| 拉丁名称: | Selaginella doederleinii |
| 使用部位: | whole herb |
| 功用: | To clear heat and resolve toxin, dispel wind and eliminate damp. |
| 适用症: | Swelling pain in throat, red eyes with gall, lung heat cough, mastitis, damp-heat jaundice, wind-damp impediment pain, bleeding due to external injury. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1617-53-4 | 穗花杉双黄酮 | Amentoflavone | 5281600 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 5951-57-5 | - | Dolichodial | 442422 |
| 23132-13-0 | Heveaflavone | Heveaflavone | 15559724 |
| 539-15-1 | 大麦芽碱 | Hordenine | 68313 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| CAT | - | 11p13 | 29179721 |
| CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | 9p24.1 | 27378243 |
| CDC37 | P50CDC37 | 19p13.2 | 21871133 |
| CDK4 | CMM3; PSK-J3 | 12q14.1 | 21871133 |
| COLQ | CMS5; EAD | 3p25.1 | 28056971 |
| CSNK2A2 | CK2A2; CK2alpha'; CSNK2A1 | 16q21 | 21871133 |
| CXCL10 | C7; IFI10; INP10; IP-10; SCYB10; crg-2; gIP-10; mob-1 | 4q21.1 | 28378188 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Blood Pressure | phenotype | 28143892 |
| Constipation | phenotype | 31714751 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Fibrosis | phenotype | 28143892 |
| Inflammation | phenotype | 27374313 |
| Irritable Bowel Syndrome | disease | 31714751 |
| Lung Neoplasms | group | 21550230 |
| Multiple Myeloma | disease | 21871133 |
| Neoplasm Metastasis | phenotype | 31182131 |
