1. 药材主信息
| 中文名称: | 大花剪秋罗 |
| 英文名称: | Brilliant Campion |
| 拉丁名称: | Lychnis fulgens |
| 使用部位: | root and whole herb |
| 功用: | To clear heat and disinhibit urine, fortify spleen, quiet spirit. |
| 适用症: | Inhibited urination, child gan accumulation, night sweating, headache, insomnia. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 465-18-9 | 猪苓酸C | (2R)-2-[(5R,10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid | 9805290 |
| 18069-14-2 | (20R,22R)-2Β,3Β,5Α,14Α,20,22,25-七羟基胆甾-7-烯-6-酮 | 2beta,3beta,5beta,14,20,22R,25-Heptahydroxycholest-7-en-6-one | 441833 |
| 3604-87-3 | - | Ecdysone | 19212 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| FOXO1 | FKH1; FKHR; FOXO1A | 13q14.11 | 31063760 |
| FOXO3 | AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A | 6q21 | 31063760 |
| HDAC8 | CDA07; CDLS5; HD8; HDACL1; KDAC8; MRXS6; RPD3; WTS | Xq13.1 | 28528906 |
| LAS1L | Las1; Las1-like; WTS; dJ475B7.2 | Xq12 | 28528906 |
| LATS1 | WARTS; wts | 6q25.1 | 28528906 |
| MAP3K5 | ASK1; MAPKKK5; MEKK5 | 6q23.3 | 31063760 |
| MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | 10q11.22 | 31063760 |
| SLCO1A2 | OATP; OATP-A; OATP1A2; SLC21A3 | 12p12.1 | 31928869 |
| YAP1 | COB1; YAP; YAP2; YAP65; YKI | 11q22.1 | 28528906 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 30120247 |
| Neoplasms | group | 30120247 |
