1. 靶点主信息
| NCBI Gene id: | 240 |
| Gene_name: | ALOX5 |
| Gene alias: | 5-LO; 5-LOX; 5LPG; LOG5 |
| Map location: | 10q11.21 |
| Type of gene: | protein-coding |
| Description: | arachidonate 5-lipoxygenase |
| OMIM_id: | 152390 |
| HGNC_id: | 435 |
| Ensembl_id: | ENSG00000012779 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 白花丹参 | Whiteflower Danshen | Salvia miltiorrhiza f. alba |
| 白花甘西鼠尾草 | Radix Salviae Przewalskii Albae | - |
| 川木通 | Armand Clematis Stem | Caulis Clematidis Armandii |
| 粗毛南蛇藤 | Hirsute Bittersweet | Celastrus strigillosus |
| 丹参 | root of Ligulilobe sage | Radix Salviae liguliobae |
| 东北雷公藤 | Radix Tripterygii regeli | - |
| 粉芭蕉 | Plantain Banana | Musa paradisiaca |
| 甘西鼠尾草 | Przewalsk Sage | Salvia przewalskii |
| 狗肉 | Dog Meat | Canis familiaris |
| 黑曼巴 | Regel Threewingnut | Tripterygium regelii |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 5957-80-2 | 鼠尾草酚 | Carnosol | 442009 |
| 34157-83-0 | 雷公藤红素 | Celastrol | 122724 |
| 96574-01-5 | 丹酚酸A | Salvianolic acid A | 5281793 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 30268831 |
| Alzheimer's Disease | disease | 24849358 |
| Arthritis | disease | 31124139 |
| Arthritis | disease | 21501142 |
| Arthritis, Experimental | disease | 22415021 |
| Brain Infarction | disease | 29540209 |
| Brain Ischemia | disease | 29540209 |
| Brain Ischemia | disease | 27609227 |
| Brain Neoplasms | group | 24810052 |
| Cardiomegaly | phenotype | 29987023 |
