1. 药材主信息
| 中文名称: | 东北雷公藤 |
| 英文名称: | Radix Tripterygii regeli |
| 拉丁名称: | - |
| 使用部位: | - |
| 功用: | - |
| 适用症: | - |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 76035-62-6 | 3-表卡通酸 | 3-Epikatonic acid | 10434225 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 34157-83-0 | 雷公藤红素 | Celastrol | 122724 |
| 86632-20-4 | orthosphenic acid | Orthosphenic acid | 20056194 |
| 71247-78-4 | 大子五层龙酸 | Salaspermic acid | 44593364 |
| 474-58-8 | 刺五加苷A(胡萝卜苷） | Sitogluside | 5742590 |
| 201534-10-3 | Triptocalline A | Triptocalline A | 44559634 |
| 142950-86-5 | TRIPTOQUINONOIC ACID A | Triptoquinone A | 132524 |
| 142937-50-6 | 雷藤二萜醌 B | Triptoquinone B | 11724191 |
| 84108-17-8 | 雷公藤三萜酸 A | Triptotriterpenic acid A | 21594203 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 31982489 |
| Abcb1a | Abcb4; Evi32; Mdr1a; Mdr3; P-gp; Pgp; Pgy-3; Pgy3; mdr-3 | 5 A1|5 3.43 cM | 31982489 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31053160 |
| ALOX5 | 5-LO; 5-LOX; 5LPG; LOG5 | 10q11.21 | 27597642 |
| ANXA5 | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 | 4q27 | 22641218 |
| BAG3 | BAG-3; BIS; CAIR-1; MFM6 | 10q26.11 | 24351928 |
| BAX | BCL2L4 | 19q13.33 | 23846217 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21506956 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21506956 |
| BSG | 5F7; CD147; EMMPRIN; EMPRIN; OK; SLC7A11; TCSF | 19p13.3 | 29987023 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 30268831 |
| Alzheimer's Disease | disease | 24849358 |
| Arthritis | disease | 31124139 |
| Arthritis | disease | 21501142 |
| Arthritis, Experimental | disease | 22415021 |
| Brain Infarction | disease | 29540209 |
| Brain Ischemia | disease | 29540209 |
| Brain Neoplasms | group | 24810052 |
| Cardiomegaly | phenotype | 29987023 |
| Edema | phenotype | 27597642 |
