1. 药材主信息
| 中文名称: | 丹参 |
| 英文名称: | root of Ligulilobe sage |
| 拉丁名称: | Radix Salviae liguliobae |
| 使用部位: | root |
| 功用: | To remove blood stasis and relieve pain, to promote the flow of blood and stimulate menstrual discharge, and to ease the mind. |
| 适用症: | Angina pectoris, cerebral atherosclerosis, diffusive intravascular clotting, thrombophlebitis, hepatitis, acute surgical infection, mastitis, erysipelas, otitis media, tonsillitis, bone marrow infection, menstrual disorder, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, pain in heart and abdomen, concretion conglomeration accumulation and gathering, heat impediment swelling and pain, knocks and falls, heat entering construction-blood, vexation and agitation, insomnia and vexation, swelling toxin of welling abscess and sore, zoster, neurodermatitis, psoriasis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 502-61-4 | α－法呢烯 | - | 5281516 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 5794-03-6 | - | (+)-Camphene | 92221 |
| 6153-17-9 | - | (-)-beta-Phellandrene | 443161 |
| 19903-73-2 | - | (-)-Epicedrol | 6713078 |
| 20126-76-5 | (-)-4-萜品醇 | (-)-Terpinen-4-ol | 5325830 |
| 115939-25-8 | 丹酚酸B | (R)-2-(((2R,3R)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid | 11629084 |
| 77769-21-2 | 1,2-二氢丹参醌 | 1,2-Dihydrotanshinquinone | 105119 |
| 21891-63-4 | - | 1,5-Dihydroxy-3-methylanthraquinone | 5316800 |
| 29477-54-1 | - | 1-(3,4-Dihydroxyphenyl)-2-hydroxyethanone | 22134444 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ACTA2 | ACTSA | 10q23.31 | 28257144 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 22154085 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 22607709 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486344 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31193821 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29789538 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Alzheimer's Disease | disease | 29158049 |
| Atherosclerosis | disease | 25572313 |
| Atherosclerosis | disease | 28736034 |
| Blood Pressure | phenotype | 28143892 |
| Bone neoplasms | group | 30691497 |
| Brain Ischemia | disease | 27609227 |
| Burkitt Lymphoma | disease | 22607709 |
| Cerebral Ischemia | disease | 31193821 |
| Chemical and Drug Induced Liver Injury | disease | 29106960 |
