科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 紫贝齿
英文名称: Purple cowrie shell
拉丁名称: Concha Mauritiae Arabicae
使用部位: -
功用: Treatment of: 1. Palpitations, irritability, insomnia, dream-disturbed sleep or infantile convulsions due to high fever. Purple cowrie shell (Zibeichi) is used with Coptis root (Huanglian), Mother-of-pearl (Zhenzhumu) and Antelope's horn (Lingyangjiao). 2. Wind and heat in the liver meridian manifested as red, swollen and painful eyes or visual obstruction, or hyperactivity of liver yang manifested as dizziness, vertigo and headache. Purple cowrie shell (Zibeichi) is used with Chrysanthemum flower (Juhua), Mulberry leaf (Sangye) and Uncaria stem (Gouteng).
适用症: Treatment of: 1. Palpitations, irritability, insomnia, dream-disturbed sleep or infantile convulsions due to high fever. Purple cowrie shell (Zibeichi) is used with Coptis root (Huanglian), Mother-of-pearl (Zhenzhumu) and Antelope's horn (Lingyangjiao). 2
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
506-52-5 1-二十六烷醇 1-Hexacosanol 68171
10091-84-6 - 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine 135438588
83-46-5 β-谷甾醇 Beta-Sitosterol 222284
83-46-5 β-谷甾醇 Beta-Sitosterol 222284
630-03-5 正二十九烷 Nonacosane 12409
83-48-7 豆甾醇 Stigmasterol 5280794

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941
BACE1 ASP2; BACE; HSPC104 11q23.3 24107941
NR1H2 LXR-b; LXRB; NER; NER-I; RIP15; UNR 19q13.33 24107776
NR1H3 LXR-a; LXRA; RLD-1 11p11.2 24107776
NR1H4 BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 12q23.1 24107776
TLR4 ARMD10; CD284; TLR-4; TOLL 9q33.1 24107776

4. 相关疾病

疾病名称 疾病类型 参考文献
Liver diseases group 24107776